Recent Activities

2016 MEM Senior Design

Team MEM-12

3D BIOFABRICATION OF A HETEROGENOUS MICRO LIVER-ON-A-CHIP

Advisor: Dr. Wei Sun, Dr. Qudus Hamid

Team:

Richard Dambra                    Biomedical Engineering

Todd Hullfish                    Mechanical Engineering

Kristina Ignasiak                Biomedical Engineering

Wisam Mohamed                    Biomedical Engineering

Jessica Nabitovsky                Biomedical Engineering

Abstract:

Pharmaceutical development is challenging; it takes an average of 12 years and over $1.2 billion dollars to bring a drug from conception to market. Tissue engineering (TE) offers unique opportunities to expedite the screening process by creating intricate cell-laden microstructures in an attempt to recapitulate the functions of human organs. TE is also capable of removing disconnects between pre-clinical animal studies and clinical trials. The objective of this senior design project is to utilize 3D bioprinting techniques to fabricate a liver micro-organ. This micro-organ serves as an in vitro testing platform to the drug development process(es). With the support of Drexel University and SunP Biotech, LLC, this team was provided with a patented multi-nozzle bioprinter, novel biomaterials, and cell culturing facilities to design a liver construct complete with; a microvascular network, multiple cell types, and a biomimetic microenvironment. This in vitro micro-organ provides a new platform to expedite drug development for patients in need.

--

Team MEM-13

3D MULTI-NOZZLE CELL DEPOSITION SYSTEM FOR TISSUE/ORGAN FABRICATION

Advisors: Dr. Wei Sun, Dr. Qudus Hamid

Team:

Justin Bianchini                Biomedical Engineering

Caleb Paioletti                    Mechanical Engineering

Marissa Seybert                    Mechanical Engineering

Abhishek Singh                    Mechanical Engineering