Recent Activities
2016 MEM Senior Design
Team MEM-12
3D BIOFABRICATION OF A HETEROGENOUS MICRO LIVER-ON-A-CHIP
Advisor: Dr. Wei Sun, Dr. Qudus Hamid
Team:
Richard Dambra Biomedical Engineering
Todd Hullfish Mechanical Engineering
Kristina Ignasiak Biomedical Engineering
Wisam Mohamed Biomedical Engineering
Jessica Nabitovsky Biomedical Engineering
Abstract:
Pharmaceutical development is challenging; it takes an
average of 12 years and over $1.2 billion dollars to bring a
drug from conception to market. Tissue engineering (TE)
offers unique opportunities to expedite the screening
process by creating intricate cell-laden microstructures in
an attempt to recapitulate the functions of human organs. TE
is also capable of removing disconnects between pre-clinical
animal studies and clinical trials. The objective of this
senior design project is to utilize 3D bioprinting
techniques to fabricate a liver micro-organ. This
micro-organ serves as an in vitro testing platform to the
drug development process(es). With the support of Drexel
University and SunP Biotech, LLC, this team was provided
with a patented multi-nozzle bioprinter, novel biomaterials,
and cell culturing facilities to design a liver construct
complete with; a microvascular network, multiple cell types,
and a biomimetic microenvironment. This in vitro micro-organ
provides a new platform to expedite drug development for
patients in need.
--
Team MEM-13
3D MULTI-NOZZLE CELL DEPOSITION SYSTEM FOR TISSUE/ORGAN
FABRICATION
Advisors: Dr. Wei Sun, Dr. Qudus Hamid
Team:
Justin Bianchini Biomedical Engineering
Caleb Paioletti Mechanical Engineering
Marissa Seybert Mechanical Engineering
Abhishek Singh Mechanical Engineering